From early-stage fundamental research to everyday clinical practice, sensors that can specifically and accurately quantify analytes from biosamples are essential analytical tools in the biomedical sciences. In medicine, for example, biomarker profiling for prognostics and diagnostics is rapidly becoming more important with the ever-growing discoveries of disease-indicating biomarkers.

Current gold-standard analytical techniques are either destructive or label-based; they require bulky and expensive equipment as well as lengthy and laborious protocols that must be run by trained experts in equipped facilities. Current trends in medicine, including personalized treatments and at-home health monitoring, require biosensing tools that are ubiquitous. Moreover, in order for medicine to benefit from the big data revolution, low-cost and decentralized biosensor networks that can rapidly measure multiple analytes from small sample volumes are needed.

In our multidisciplinary group, we conduct basic, applied, and translational research at the cross-sections of photonics, nanotechnology and biomedical sciences towards the development of novel instruments that will impact next-generation healthcare practice and foundational biomedical research. We benefit from a variety of disciplines, including physical, chemical, material, data and life sciences, to i) engineer optical biochemical nanosensors, molecular identification and imaging systems, ii) enhance the analytical performance of current technology,  and iii) develop field-deployable and cost-effective tools for applications including molecular analytics, diagnostics, therapeutics, and global health.

For publications, see Prof. Yesilkoy’s Google Scholar.